Archive for April 2017

Coronary heart disease

Saturated fat does not clog the arteries: coronary heart disease is a chronic inflammatory condition, the risk of which can be effectively reduced from healthy lifestyle interventions.

Coronary artery disease pathogenesis and treatment urgently requires a paradigm shift.

Despite popular belief among doctors and the public, the conceptual model of dietary saturated fat clogging a pipe is just plain wrong.

A landmark systematic review and meta-analysis of observational studies showed no association between saturated fat consumption and
all-cause mortality, coronary heart disease (CHD),
CHD mortality, ischaemic stroke or type 2 diabetes in healthy adults. Similarly in the secondary prevention of CHD there is no benefit from reduced fat, including saturated fat, on myocardial infarction, cardiovascular or all-cause mortality.

It is instructive to note that in an angiographic study of postmenopausal women with CHD, greater intake of saturated fat was associated with less progression of atherosclerosis whereas carbohydrate and polyunsaturated fat intake were associated with greater progression.

Preventing the development of atherosclerosis is important but it is atherothrombosis that is the real killer.

The inflammatory processes that contribute to cholesterol deposition within the artery wall and subsequent plaque formation (atherosclerosis), more closely resembles a ‘pimple’ (figure 1). Most cardiac events occur at sites with <70% coronary artery obstruction and these do not generate ischaemia on stress testing.4 When plaques rupture (analogous to a pimple bursting), coronary thrombosis and myocardial infarction can occur within minutes.

The limitation of the current plumbing approach (‘unclogging a pipe’) to the management of coronary disease is revealed by a series of randomised controlled trials (RCTs) which prove that stenting significantly obstructive stable lesions fail to prevent myocardial infarction or to reduce mortality.


Figure 1
Lifestyle interventions for the prevention and treatment of coronary disease.
Dietary RCTs with outcome benefit in primary and secondary prevention.
In comparison with advice to follow a ‘low fat’ diet (37% fat), an energy-unrestricted Mediterranean diet (41% fat) supplemented with at least four tablespoons of extra virgin olive oil or a handful of nuts (PREDIMED) achieved a significant 30% (number needed to treat (NNT)=61) reduction in cardiovascular events in over 7500 high-risk patients.

Furthermore, the Lyon Heart study showed that adopting a Mediterranean diet in secondary prevention improved hard outcomes for both recurrent myocardial infarction (NNT=18) and all-cause mortality (NNT=30), despite there being no significant difference in plasma low-density lipoprotein (LDL) cholesterol between the two groups.

Thank It is the alpha linoleic acid, polyphenols and omega-3 fatty acids present in nuts, extra virgin olive oil, vegetables and oily fish that rapidly attenuate inflammation and coronary thrombosis.

Both control diets in these studies were relatively healthy, which make it highly likely that even larger benefits would be observed if the Mediterranean diets discussed above were compared with a typical western diet.

LDL cholesterol risk has been exaggerated
Decades of emphasis on the primacy of lowering plasma cholesterol, as if this was an end in itself and driving a market of ‘proven to lower cholesterol’ and ‘low-fat’ foods and medications, has been misguided. Selective reporting may partly explain this misconception.

Reanalysis of unpublished data from the Sydney Diet Heart Study and the Minnesota coronary experiment reveal replacing saturated fat with linoleic acid containing vegetable oils increased mortality risk despite significant reductions in LDL and total cholesterol (TC).

A high TC to high-density lipoprotein (HDL) ratio is the best predictor of cardiovascular risk (hence this calculation, not LDL, is used in recognised cardiovascular risk calculators such as that from Framingham).

A high TC to HDL ratio is also a surrogate marker for insulin resistance (ie, chronically elevated serum insulin at the root of heart disease, type 2 diabetes and obesity). And in those over 60 years, a recent systematic review concluded that LDL cholesterol is not associated with cardiovascular disease and is inversely associated with all-cause mortality.

A high TC to HDL ratio drops rapidly with dietary changes such as replacing refined carbohydrates with healthy high fat foods.

A simple way to combat insulin resistance (chronically high levels of serum insulin) and inflammation.

Compared with physically inactive individuals, those who walk briskly at or above 150 min/week can increase life expectancy by 3.4–4.5 years independent of body weight.

Regular brisk walking may also be more effective than running in preventing coronary disease. And just 30 min of moderate activity a day more than three times/week significantly improves insulin sensitivity and helps reverse insulin resistance (ie, lowers the chronically elevated levels of insulin that are associated with obesity) within months in sedentary middle-aged adults.

This occurs independent of weight loss and suggests even a little activity goes a long way.
Another risk factor for CHD is environmental stress. Childhood trauma can lead to an average decrease in life expectancy of 20 years.

Chronic stress increases glucocorticoid receptor resistance, which results in failure to down regulate the inflammatory response.

Combining a complete lifestyle approach of a healthful diet, regular movement and stress reduction will improve quality of life, reduce cardiovascular and all-cause mortality.

It is time to shift the public health message in the prevention and treatment of coronary artery disease away from measuring serum lipids and reducing dietary saturated fat. Coronary artery disease is a chronic inflammatory disease and it can be reduced effectively by walking 22 min a day and eating real food.

There is no business model or market to help spread this simple yet powerful intervention.



Our cerebrum discharges a neurotransmitter called dopamine. It is vital for the correct working of different organs in our body.
▪ It is powerful in our body in the accompanying ways:
▪ It controls the discharge of prolactin.
▪ It helps in directing body development.
▪ It helps in enhancing your intellectual capacities (i.e. consideration, information, assessment, memory, basic leadership and critical thinking abilities)
▪ It controls the focal point of delight and reward in your cerebrum.
At the point when the dopamine level in our body is decreased it could prompt to:
▪ Misery
▪ Despondency
▪ Antagonism
▪ State of mind swings

To keep away from these medical problems, you should raise your dopamine level and you can do this in these 10 viable ways.

A development of microscopic organisms and poisons in the body can debilitate your invulnerable framework and lower the dopamine generation in the body. You ought to consistently detoxify your body and free it of these unsafe poisons.

When you practice, you raise your endorphin, serotonin and dopamine levels. You will feel fit, sound, upbeat and peaceful.

You ought to abstain from being dependent on;
▪ Betting
▪ Liquor
▪ Drugs
▪ Sex

These addictions just give a brief settle to our anxiety and sorrow. Addictions change our way of life and suit it to our wellspring of enslavement. You ought to have a go at taking part in side interests and work that makes you upbeat.

Tyrosine is an amino corrosive which is only one out of 22 fundamental amino acids that are useful in the generation of proteins. It is likewise a key substance for dopamine generation.

You can raise your tyrosine levels when you devour avocados, dull chocolate, green tea and watermelons.

When you tune in to music your dopamine levels increment for a brief span, so you ought to tune in to music every now and again to calm anxiety and misery.

Your dopamine level increments when you take part as a main priority entrusting and aptitude required exercises, for example, painting, designing, cooking, auto repair, sewing, composing, moving and singing.

When you are sorted out you have a sentiment fulfillment and this is on the grounds that your dopamine levels will be raised. You can record your everyday errands and execute them one by one.

When you do things constantly and you aren’t fruitful in these assignments your dopamine level will ascend as you have a feeling of achievement.

This type of practice is awesome for raising your dopamine level and it enhances your state of mind and helps you to unwind.

When you take certain supplements your dopamine level will increment.
These supplements include:
▪ Ginkgo Biloba
▪ Curcumin which is a dynamic segment in turmeric can raise your dopamine level.
▪ L-theanine is known to bring a few neurotransmitters up in the cerebrum and dopamine is one of such neurotransmitters. You can get this compound from green tea.
▪ Acetyl-l-tyrosine underpins the generation of dopamine

Bionic Eye Lens

A new bionic eye lens currently in development would give humans 3x 20/20 vision, at any age.
The lens, named the Ocumetics Bionic Lens, was developed by Dr. Garth Webb, an optometrist in British Columbia who was looking for a way to optimize eyesight regardless of a person’s health or age. With this remarkable lens, patients would have perfect vision, ending the need for driving glasses, progressive lenses, and contacts, all of which are set to become a dim memory as the eye-care industry is transformed, CBC reports. Even better is the fact that people who get the lens surgically inserted will never get cataracts, because the lens replaces that of their natural eye, which inevitably decays over time. Webb says that anyone over the age of 25 is the best candidate, because that is when the eye is fully developed.
“This is vision enhancement that the world has never seen before,” he says, “If you can just barely see the clock at 10 feet, when you get the Bionic Lens you can see the clock at 30 feet away.“

The lens, which would be custom-made, is folded like a taco in a saline-filled syringe and placed in the eye, where it unravels itself within 10 seconds.

Dr. Garth Webb says the bionic lens would allow people to see to infinity and replace the need for eyeglasses and contact lenses. Webb says that the surgery can be done within 8 minutes and immediately corrects a patient’s vision. The project has been in the works for the last eight years, Webb told CBC, costing about $3 million in research and development fees, along with the acquisition of international patents and the securing of a biomedical manufacturing facility in Delta, B.C.
His mission is fueled by the “obsession” he’s had to free himself and others from corrective lenses since he was in Grade 2, when he was saddled with glasses.
“My heroes were cowboys, and cowboys just did not wear glasses,” Webb says.
Webb’s efforts were recently recognized after he presented the lens to 14 top ophthalmologists in San Diego during a gathering of the American Society of Cataract and Refractive Surgery.
Surgeons from all around the world were intrigued by his “clever” design, Webb says.
“I think this device is going to bring us closer to the holy grail of excellent vision at all ranges — distant, intermediate and near,” said Dr. Vincent DeLuise, an ophthalmologist who teaches at both Yale University and Weill Cornell Medical College in New York.

Pending clinical trials on animals and then blind human eyes, the Bionic Lens could be available in Canada and elsewhere in about two years, depending on regulatory processes in various countries, Webb says. Webb is hopeful that his lens will do away with the need for laser eye surgery, a procedure that still isn’t as efficient as it could be.
“Perfect eyesight should be a human right,” he says.

Control Diabetes With These 11 Foods

When suffering from diabetes, choosing what to eat every day can be a real challenge. Although there are many delicious foods, many of them are not suitable for your condition. If you choose the right foods, you can control your blood sugar level and thus prevent diabetes complications.

You fight and control your diabetes simply with the food you consume.
These 11 foods will help you fight diabetes and prevent its complications.

1. Kale
Kale is one of the healthiest and the most nutritious green in existence. It is rich in lutein, an important carotenoid which is extremely good for the eyes.
This property is especially important for people who suffer from diabetes because they may experience eye problems as complications of the disease. Kale is also high in fiber, iron, B vitamins, vitamin C, and calcium.

2. Nuts
Nuts are celebrated for their countless benefits, and they offer lots of nutrition for your body. They can improve the blood sugar control, especially in type 2 diabetes. They make the artery walls more flexible thus preventing blood clots.

3. Chocolate
Dark chocolate improves insulin sensitivity and helps in the prevention and treatment of type 2 diabetes. Also, dark chocolate significantly lowers blood pressure, reduces bad cholesterol and improves the blood vessel function. However, make sure you do not overdo it because it abounds in calories and fats.

4. Beans
These nutritional powerhouses are the perfect ingredient for salads, soups, and many other dishes. They offer lots of nutrition and reduce the risk of heart disease and diabetes. They are packed with fiber, which slows down the release of glucose into your bloodstream. This would prevent the blood sugar spikes and the feeling of hunger.

5. Blueberries
These sweet and nutritious berries abound in a high level of fiber which reduces the risk of cognitive decline and diabetes. They are rich in anthocyanins, specific antioxidants which according to recent research lower the risk of type 2 diabetes.

6. Barley
Barley is one of the healthiest cereal grain that is found in bread, beverages and some dishes. It can balance your blood sugar level and keep you satiated for longer. Also, barley contains a modest amount of calcium.

7. Salmon
Salmon is an important source of vitamin D, omega-3 fatty acids, and healthy fats that lower the risk of heart diseases, reduce inflammation, shape your waistline and improve insulin resistance.

8. Dairy
Dairy products abound in vitamin D and calcium, an important combination for treatment of diabetes.

9. Oats.
Nothing will give you strength and energy as a bowl of oatmeal. Oats are rich in fiber which can lower bad cholesterol and improve insulin resistance.

10. Oranges
According to many studies, people who suffer from diabetes have a low level of vitamin C in their bodies. So, make sure you eat more oranges and get the most vitamin C of them.

11. Soy Bean
Soy is loaded with high-quality protein that contains a low level of cholesterol and saturated fat.